Transitional care in geriatric patients
- Universiteit Universiteit Utrecht
- Promovendus Lotte Falke
- Promoters Toine Egberts, Marcel Bouvy
- Co-Promoters Fatma Karapinar, Wilma Knol
- Jaar 2022-2028
Financiering UU/docentschap.
Financiering UU/docentschap.
All people living with HIV need life-long treatment with antiretroviral therapy (ART). However, ART coverage in children living with HIV continues to lag behind adults and many paediatric patients in sub-Saharan Africa still do not receive optimal paediatric treatment formulations or state-of-the-art drugs. Studies of efficacy and safety of these drugs in children have lagged behind, and the full range of appropriate formulations to treat younger children are yet to be developed for both first- and second-line treatments.
Het optimaliseren van de antivirale behandeling van kinderen met HIV in Afrika door verdieping in de PK/PD van deze middelen, nieuwe formuleringen en het voorspellen van de PK middels modelleren.
A prospective observational PK/PD to study the target attainment for β-lactam antibiotics in critically ill pediatric patients and associated risk factors.