Promotie onderzoek

1. Cost benefit analysis clinical medication reviews
2. Follow up of interventions from clinical pharmacists.
3. Medication information needs of hospitalized patients.

1. Stress-relieving: 3D printing personalized cortisol for patients with adrenal insufficiency
2. A novel delayed release hydrocortison formulation for patients with adrenal insufficiency
3. Feasibility study of 10 mg 3D printed systained release hydrocortisone 
4. Feasibility study of 3D printed delayed release hydrocortisone 
5. RCT of novel 3D printed hydrocortisone vs standard of care in adrenal insufficiency 

A prospective observational PK/PD to study the target attainment for β-lactam antibiotics in critically ill pediatric patients and associated risk factors.

Hospital expenditure of expensive drugs increases yearly. In addition, shortages are becoming more common. To assure access to healthcare and treatment in the future, sustainable use of expensive drugs is very important. This research aims to optimize treatment with regard to efficacy and safety, while aiming to reduce drug costs. 
 

The aim of this project is to achieve more effective patient treatments with antibiotics by quantifying the concentrations at the site of infection with minimal sample volumes. To enable quantification of antibiotics at the site of infection, multiple assays should be developed and validated in these infected matrices, such as synovial fluid, synovial tissue, bone, and vitreous humor. Furthermore, the focus will be on small-volume samples and more patient friendly, and sustainable sample preparations.
 

A prospective observational PK/PD to study the target attainment for β-lactam antibiotics in critically ill pediatric patients and associated risk factors.