Promotie onderzoek

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Er zijn102resultaten gevonden
Medicatieveiligheid

The metabolisation of drugs as a factor in the development of adverse drug reactions

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus N. Jessurun
  • Promoters Prof dr E.P. van Puijenbroek Prof dr R.J. van Marum
  • Co-Promoters Dr H.J. Derijks Dr K Grootens
  • Jaar 2018-2022

The aim of this PhD is to study the role of drug metabolism in adverse drug reactions (ADRs), an area which is not often taken into account in pharmacovigilance. The role of metabolites in ADRs is studied by focusing on (but not limiting to) a number of  therapeutic drug groups.

Communicatie

Communicatie in de apotheek in moeilijke situaties

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus Laura Schackmann
  • Promoters Liset van Dijk
  • Co-Promoters Marcia Vervloet Ellen Koster
  • Jaar 2021-2023

Onderzoek naar verbeteren van communicatie bij wisselen van medicatie en in andere uitdagende situaties (laaggeletterdheid, emoties).

Farmacokinetiek en -dynamiek

Computational modeling of tumor growth and clonal evolution

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Anyue Yin
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Dirk Jan Moes
  • Jaar 2017-2022

Use population PK/PD modeling approach and consider evolving resistance development to better understand the development of drug resistance in anti-cancer treatments and to optimize and individualize anti-cancer treatment.

Klinische farmacologie

Personalised drug repositioning using gene expression

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Michel Koudijs
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Stefan Boehringer
  • Jaar 2017-2022

Drug repositioning is the application of existing drugs to new indications. We want to find out if it is possible to find new potentially effective drugs against individual tumors based on their unique gene expression patterns.

Farmacogenetica

Personalised medicine in the outpatient pharmacy

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Amar Levens
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Jesse Swen Dr Dirk Jan Moes
  • Jaar 2021- 2025
Farmacokinetiek en -dynamiek

Treosulfan pharmacokinetics and dynamics in pediatric allogeneic stem cell transplantation

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Eileen van der Stoep
  • Promoters Prof Dr Arjan Lankester Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr J Zwaveling
  • Jaar 2015-2022

Treosulfan is increasingly used in pediatric allogeneic HSCT. Pharmacokinetic data in children is sparse. Also the relationship with acute and late toxicity and clinical outcome is not clear yet. Our aim is to establish a popPK model, investiate the relationship between treosulfan exposure and outcome and to acquire knowledge about the acute and late side effects. 

Klinische farmacologie

Bariatrische chirurgie en HIV

  • Universiteit Radboud UMC Nijmegen
  • Promovendus Leena Zino
  • Promoters David Burger
  • Co-Promoters Angela Colbers Olivier Richel
  • Jaar 2020 - 2023
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