Productzorg en bereiding
3D printing of pharmaceutical preparations
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Iris Lafeber
- Promoters Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr Kirsten Schimmel
- Jaar 2020-2024
KNMP stelt wetenschappelijk onderzoek voorop. Hier kunt u de meest recente onderzoeken vinden.
Er zijn22resultaten gevonden
Klinische farmacologie
Retroperitoneal fibrosis
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Hardjit Kharagjitsing
- Promoters Prof Dr Teun van Gelder
- Jaar 2020-2023
Farmacogenetica
Treatment and genetics of RA
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Frank Eektimmerman
- Promoters Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr Jesse Swen
- Jaar 2015-2022
Farmacokinetiek en -dynamiek
Computational modeling of tumor growth and clonal evolution
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Anyue Yin
- Promoters Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr Dirk Jan Moes
- Jaar 2017-2022
Use population PK/PD modeling approach and consider evolving resistance development to better understand the development of drug resistance in anti-cancer treatments and to optimize and individualize anti-cancer treatment.
Klinische farmacologie
Personalised drug repositioning using gene expression
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Michel Koudijs
- Promoters Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr Stefan Boehringer
- Jaar 2017-2022
Drug repositioning is the application of existing drugs to new indications. We want to find out if it is possible to find new potentially effective drugs against individual tumors based on their unique gene expression patterns.
Farmacogenetica
Personalised medicine in the outpatient pharmacy
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Amar Levens
- Promoters Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr Jesse Swen Dr Dirk Jan Moes
- Jaar 2021- 2025
Farmacokinetiek en -dynamiek
Treosulfan pharmacokinetics and dynamics in pediatric allogeneic stem cell transplantation
- Universiteit Leiden Universitair Medisch Centrum
- Promovendus Eileen van der Stoep
- Promoters Prof Dr Arjan Lankester Prof Dr Henk-Jan Guchelaar
- Co-Promoters Dr J Zwaveling
- Jaar 2015-2022
Treosulfan is increasingly used in pediatric allogeneic HSCT. Pharmacokinetic data in children is sparse. Also the relationship with acute and late toxicity and clinical outcome is not clear yet. Our aim is to establish a popPK model, investiate the relationship between treosulfan exposure and outcome and to acquire knowledge about the acute and late side effects.
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