Promotie onderzoek

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Er zijn47resultaten gevonden
Farmacokinetiek en -dynamiek

The impact of continuous renal replacement therapy and hyperinflammation on the pharmacokinetics in intensive care unit patients

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Tim Smeets
  • Promoters prof. dr. Birgit Koch prof. dr. Diederik Gommers
  • Co-Promoters dr. Nicole G.M. Hunfeld dr. Henrik Endeman
  • Jaar 2021-2023
  1. To study the impact of inflammation on midazolam pharmacokinetics in critically ill covid-19 patients.
  2. To study the impact of continuous renal replacement therapy on target attainment and pharmacokinetics of drugs in critically ill patients.
Medicatieveiligheid

Sexual adverse drug reactions

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Rineke Gordijn
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Martina Teichert
  • Jaar 2020-2022
Productzorg en bereiding

3D printing of pharmaceutical preparations

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Iris Lafeber
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Kirsten Schimmel
  • Jaar 2020-2024
Klinische farmacologie

Retroperitoneal fibrosis

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Hardjit Kharagjitsing
  • Promoters Prof Dr Teun van Gelder
  • Jaar 2020-2023
Farmacogenetica

Treatment and genetics of RA

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Frank Eektimmerman
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Jesse Swen
  • Jaar 2015-2022
Farmacokinetiek en -dynamiek

Computational modeling of tumor growth and clonal evolution

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Anyue Yin
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Dirk Jan Moes
  • Jaar 2017-2022

Use population PK/PD modeling approach and consider evolving resistance development to better understand the development of drug resistance in anti-cancer treatments and to optimize and individualize anti-cancer treatment.

Klinische farmacologie

Personalised drug repositioning using gene expression

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Michel Koudijs
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Stefan Boehringer
  • Jaar 2017-2022

Drug repositioning is the application of existing drugs to new indications. We want to find out if it is possible to find new potentially effective drugs against individual tumors based on their unique gene expression patterns.

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