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Er zijn16resultaten gevonden
Farmacokinetiek en -dynamiek

Dose individualization of Beta-lactam and Ciprofloxacin in ICU patients: To TDM or not to TDM

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Alan Abdulla
  • Promoters Birgit Koch
  • Co-Promoters Rik Endeman Anouk Muller
  • Jaar 2018 - 2022
  • A prospective observational PK/PD to study the target attainment for β-lactam antibiotics in critical ill patients and its associated risk factors.
  • A multi-centre, randomised controlled trial to assess the efficacy and cost-effectiveness of model-based TDM of beta-lactam and fluoroquinolone antibiotics.
Farmacokinetiek en -dynamiek

PK/PD of betalactamantibiotics

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Eveline Roelofsen
  • Promoters Birgit Koch
  • Co-Promoters Brenda de Winter Anouk Muller
  • Jaar 2019 - 2023
  1. Optimasation of the flucloxacillin absorptiontest.
  2. PK modeeling of cefotaxim in critically ill patients.
  3. PK modeling of flucloxacillin in mice.
Medicatieveiligheid

Clinical rules in de huiartsenpraktijk

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Fauzia Chitanie
  • Promoters Hugo van der Kuy
  • Co-Promoters Floor van Rosse Kees van Boven
  • Jaar 2019 - 2024

Meerwaarde van clinical rules in de eerste lijn.

Medicatieveiligheid

Alert Fatigue

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Bob van der Loo
  • Promoters Hugo van der Kuy
  • Co-Promoters Heleen van der Sijs
  • Jaar 2020 - 2024

Optimalisatie van het clinical decision support system.

Therapietrouw

Resistant HYpertension: MEasure To ReaCh Targets (RHYME-RCT)

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Laura Peeters
  • Promoters Prof. dr. Teun van Gelder
  • Co-Promoters Dr. B.C.P. Koch Dr. J. Versmissen
  • Jaar 2018 - 2022

RHYME-RCT is a multi-center randomized controlled trial to identify and improve non-adherence in patients with resistant hypertension and are included from 10 peripheral and 2 academic hospitals. Non-adherence is measured by means of a validated dried blood spot method. This method includes 17 antihypertensive drugs from different drug classes.

Farmacokinetiek en -dynamiek

Pharmacometric analyses of systemic therapies within oncology

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Bram Agema
  • Promoters prof. dr. Ron Mathijssen prof. dr. Birgit Koch
  • Co-Promoters Stijn Koolen
  • Jaar 2020-2024

Het onderzoeken van PK/PD relaties middels farmacometrische modellen en de implicaties daarvan op de dagelijkse klinische praktijk op de afdeling oncologie.

Medicatieveiligheid

Effect of centralising medication distribution on medication safety in hospitals

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Janique Jessurun
  • Promoters prof. dr. Patricia van den Bemt prof. dr. Monique van Dijk
  • Co-Promoters dr. Nicole Hunfeld
  • Jaar 2017-2022

The aim of the thesis is to identify and examine strategies regarding the preparation and administration of medication to improve medication safety in hospitals. Examined interventions:

  1. central automated dose dispensing combined with barcode-assisted medication administration,
  2. a pharmacy-based centralised intravenous admixture service.
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