Promotie onderzoek

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Er zijn18resultaten gevonden
Farmacokinetiek en -dynamiek

Artificial Intelligence and Structure-Based Approaches to Characterize the Role of Selected Membrane Proteins in Breast Cancer

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Marina Gorostiola Gonzalez
  • Promoters A.P. IJzerman
  • Co-Promoters G. van Westen L. Heitman
  • Jaar 2019 - 2023

Onderzoek in Spanje

Farmacokinetiek en -dynamiek

Model based optimization of immunosuppressive therapy in kidney transplant recipients

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Tom Zwart
  • Promoters Henk-Jan Guchelaar Hans de Fijter
  • Co-Promoters Dirk Jan Moes
  • Jaar 2018 - 2022

Het onderzoek is gericht op het verbeteren van immuunsupressieve therapie bij niertransplantatiepatiënten met behulp van PK-PD modelling.

Farmacokinetiek en -dynamiek

Quantitative and miniaturized assays for structure-resolved lipidomics in metabolic diseases

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Madhulika Singh
  • Promoters T. Hankemeier
  • Co-Promoters A. Harms
  • Jaar 2019 - 2023

Onderzoek in India

Farmacokinetiek en -dynamiek

Bioanalysis and Biotransformation of Covalent Targeted Kinase Inhibitors in Oncology

  • Universiteit Universiteit Utrecht
  • Promovendus Irene Retmana
  • Promoters Beijnen
  • Co-Promoters Sparidans
  • Jaar 2020 - 2024
Farmacokinetiek en -dynamiek

Biobased factor VIII therapies in hemophilia A patients

  • Universiteit Universiteit Utrecht
  • Promovendus Anouk Donners
  • Promoters Toine Egberts
  • Co-Promoters Karin Rademaker Erik van Maarseveen
  • Jaar 2018 - 2022

The landscape of drug development as well as clinical practice has been changing  over the last decennium, with the increasing availability and use of biobased therapies. This research is now focusing on the use and therapeutic drug monitoring of biobased factor VIII therapies in hemophilia A patients.

Geneesmiddelregulering

Safety assessment and use of biologicals/ biosimilars in clinical practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rosanne Meijboom
  • Promoters Toine Egberts Bert Leufkens
  • Co-Promoters Thijs Giezen Helga Gardarsdottir
  • Jaar 2018 - 2022

The aim of this project is to provide insight in the use of biologicals, including biosimilars, in clinical practice and add to the safe and effective use of these agents. We also provide guidance on the implementation of biosimilars in clinical practice from the perspective of different stakeholders including prescribers, pharmacists and patients.

Farmacokinetiek en -dynamiek

Dose individualization of Beta-lactam and Ciprofloxacin in ICU patients: To TDM or not to TDM

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Alan Abdulla
  • Promoters Birgit Koch
  • Co-Promoters Rik Endeman Anouk Muller
  • Jaar 2018 - 2022
  • A prospective observational PK/PD to study the target attainment for β-lactam antibiotics in critical ill patients and its associated risk factors.
  • A multi-centre, randomised controlled trial to assess the efficacy and cost-effectiveness of model-based TDM of beta-lactam and fluoroquinolone antibiotics.
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