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Er zijn30resultaten gevonden
Farmacokinetiek en -dynamiek

Artificial Intelligence and Structure-Based Approaches to Characterize the Role of Selected Membrane Proteins in Breast Cancer

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Marina Gorostiola Gonzalez
  • Promoters A.P. IJzerman
  • Co-Promoters G. van Westen L. Heitman
  • Jaar 2019 - 2023

Onderzoek in Spanje

Farmacokinetiek en -dynamiek

Model based optimization of immunosuppressive therapy in kidney transplant recipients

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Tom Zwart
  • Promoters Henk-Jan Guchelaar Hans de Fijter
  • Co-Promoters Dirk Jan Moes
  • Jaar 2018 - 2022

Het onderzoek is gericht op het verbeteren van immuunsupressieve therapie bij niertransplantatiepatiënten met behulp van PK-PD modelling.

Farmacokinetiek en -dynamiek

Quantitative and miniaturized assays for structure-resolved lipidomics in metabolic diseases

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Madhulika Singh
  • Promoters T. Hankemeier
  • Co-Promoters A. Harms
  • Jaar 2019 - 2023

Onderzoek in India

Farmacokinetiek en -dynamiek

Bioanalysis and Biotransformation of Covalent Targeted Kinase Inhibitors in Oncology

  • Universiteit Universiteit Utrecht
  • Promovendus Irene Retmana
  • Promoters Beijnen
  • Co-Promoters Sparidans
  • Jaar 2020 - 2024
Farmaco-epidemiologie

Bridging marketing authorisation studies with population-based registries to value medicine in daily practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rawa Ismail
  • Promoters Prof. dr. A. de Boer
  • Co-Promoters Dr. M. van Dartel Dr. D. Hilaris Dr. M. Wouters
  • Jaar 2019 - 2023

Research directed at melanoma en lung cancer registries

Farmacokinetiek en -dynamiek

Biobased factor VIII therapies in hemophilia A patients

  • Universiteit Universiteit Utrecht
  • Promovendus Anouk Donners
  • Promoters Toine Egberts
  • Co-Promoters Karin Rademaker Erik van Maarseveen
  • Jaar 2018 - 2022

The landscape of drug development as well as clinical practice has been changing  over the last decennium, with the increasing availability and use of biobased therapies. This research is now focusing on the use and therapeutic drug monitoring of biobased factor VIII therapies in hemophilia A patients.

Geneesmiddelregulering

Safety assessment and use of biologicals/ biosimilars in clinical practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rosanne Meijboom
  • Promoters Toine Egberts Bert Leufkens
  • Co-Promoters Thijs Giezen Helga Gardarsdottir
  • Jaar 2018 - 2022

The aim of this project is to provide insight in the use of biologicals, including biosimilars, in clinical practice and add to the safe and effective use of these agents. We also provide guidance on the implementation of biosimilars in clinical practice from the perspective of different stakeholders including prescribers, pharmacists and patients.

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