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Er zijn8resultaten gevonden
Farmaco-epidemiologie

Bridging marketing authorisation studies with population-based registries to value medicine in daily practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rawa Ismail
  • Promoters Prof. dr. A. de Boer
  • Co-Promoters Dr. M. van Dartel Dr. D. Hilaris Dr. M. Wouters
  • Jaar 2019 - 2023

Research directed at melanoma en lung cancer registries

Geneesmiddelregulering

Safety assessment and use of biologicals/ biosimilars in clinical practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rosanne Meijboom
  • Promoters Toine Egberts Bert Leufkens
  • Co-Promoters Thijs Giezen Helga Gardarsdottir
  • Jaar 2018 - 2022

The aim of this project is to provide insight in the use of biologicals, including biosimilars, in clinical practice and add to the safe and effective use of these agents. We also provide guidance on the implementation of biosimilars in clinical practice from the perspective of different stakeholders including prescribers, pharmacists and patients.

Farmaco-epidemiologie

Effectieve interventies in reduceren vermijdbare schade door geneesmiddelgebruik bij kwetsbare ouderen

  • Universiteit Universiteit Utrecht
  • Promovendus Bastiaan Sallevelt
  • Promoters Toine Egberts Eugene van Puijenbroek
  • Co-Promoters Ingeborg Wilting Wilma Knol
  • Jaar 2018 - 2022

Onderzoek gericht op effectieve interventies in detectie en reductie van drug-related problems (DRPs) bij kwetsbare ouderen in tweedelijnszorg. Centraal staat de vraag hoe implementatie van screening tools kan bijdragen aan effectieve zorg op de juiste plaats (targeted pharmaceutical care). Onderdeel hiervan is de ontwikkeling en effectiviteitsevaluatie van een clinical decision support tool in de optimalisatie van farmacotherapie bij ouderen.

Geneesmiddelregulering

Healthcare professionals’ views on clinical relevance of new medicines in primary care

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus Marloes Dankers
  • Promoters prof. dr. Liset van Dijk prof. dr. Aukje Mantel-Teeuwisse
  • Co-Promoters dr. Marjorie Nelissen
  • Jaar 2019 - 2023

New medicines are evaluated by registration authorities in order to assess their benefit-risk-balance. However, not every new medicine has to have an added therapeutic value compared to already available medicines. The real clinical relevance of new medicine is therefore sometimes unclear. In this research project, we want to investigate the views of healthcare professionals (HCPs) on clinical relevance of new medicines in primary care. We will discuss healthcare professionals’ views on clinical relevance of new COPD and T2DM medicines and also describe the reasons for prescribing new medicines, which is often not in line with guideline recommendations. Finally, we want to investigate how healthcare professionals assess the clinical relevance of medicines that obtained market access in the last years, and to investigate which pharmaceutical gaps (in other words: which diseases cannot be properly treated and would demand new therapies) HCPs identify in their daily practice. 

Productzorg en bereiding

Pharmaceutical 3D printing: from product development to clinical assessment

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Sejad Ayyoubi
  • Promoters prof. dr. Hugo van der Kuy
  • Co-Promoters dr. E.J. (Liesbeth) Ruijgrok
  • Jaar 2021-2025
  1. Stress-relieving: 3D printing personalized cortisol for patients with adrenal insufficiency
  2. A novel delayed release hydrocortison formulation for patients with adrenal insufficiency
  3. Feasibility study of 10 mg 3D printed systained release hydrocortisone 
  4. Feasibility study of 3D printed delayed release hydrocortisone 
  5. RCT of novel 3D printed hydrocortisone vs standard of care in adrenal insufficiency 
Productzorg en bereiding

3D printing of pharmaceutical preparations

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Iris Lafeber
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters Dr Kirsten Schimmel
  • Jaar 2020-2024
Productzorg en bereiding

Microbiologische kwaliteit van de aseptische bereiding

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus Frits Boom
  • Promoters D.J. Touw
  • Co-Promoters dr. Paul le Brun
  • Jaar 2019 - 2023

Onderzoeken van risico factoren die de microbiologische kwaliteit van de aseptische bereiding bepalen en welke beheersmaatregelen getroffen kunnen worden..

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