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Er zijn3resultaten gevonden
Farmacogenetica

Pharmacogenetics of platinumbased chemotherapy in non-small cell lung cancer

  • Universiteit Universiteit Utrecht
  • Promovendus Corine de Jong
  • Promoters Toine Egberts
  • Co-Promoters Judith Herder Vera Deneer
  • Jaar 2018 - 2022

Identificeren van biomarkers, waaronder genetische variaties, die geassocieerd zijn met de effectiviteit en toxiciteit van platinumhoudende chemotherapie in de behandeling van patiënten met niet-kleincellig longcarcinoom.

Geneesmiddelregulering

Safety assessment and use of biologicals/ biosimilars in clinical practice

  • Universiteit Universiteit Utrecht
  • Promovendus Rosanne Meijboom
  • Promoters Toine Egberts Bert Leufkens
  • Co-Promoters Thijs Giezen Helga Gardarsdottir
  • Jaar 2018 - 2022

The aim of this project is to provide insight in the use of biologicals, including biosimilars, in clinical practice and add to the safe and effective use of these agents. We also provide guidance on the implementation of biosimilars in clinical practice from the perspective of different stakeholders including prescribers, pharmacists and patients.

Therapietrouw

Resistant HYpertension: MEasure To ReaCh Targets (RHYME-RCT)

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Laura Peeters
  • Promoters Prof. dr. Teun van Gelder
  • Co-Promoters Dr. B.C.P. Koch Dr. J. Versmissen
  • Jaar 2018 - 2022

RHYME-RCT is a multi-center randomized controlled trial to identify and improve non-adherence in patients with resistant hypertension and are included from 10 peripheral and 2 academic hospitals. Non-adherence is measured by means of a validated dried blood spot method. This method includes 17 antihypertensive drugs from different drug classes.