Clinical Pharmacology of cystic fibrosis transmembrane conductance regulators (CFTRs)
- Universiteit Universiteit van Amsterdam
- Promovendus Steffie Vonk
- Promoters Ron Mathot, Anke-Hilse Maitland-van der Zee
- Co-Promoters Marleen Kemper
- Jaar 2020-2025
(PB)PK modellen van antikankergeneesmiddelen in kinderen met ALL, inclusief maturatie met behulp van longitudinale analyse.
Wat is het effect van CYP2A1 remming op de bijwerkingen van clozapine.
Bestudering van de post-mortale verdeling van geneesmiddelen.
Bestudering van de post-mortale verdeling van geneesmiddelen.
All people living with HIV need life-long treatment with antiretroviral therapy (ART). However, ART coverage in children living with HIV continues to lag behind adults and many paediatric patients in sub-Saharan Africa still do not receive optimal paediatric treatment formulations or state-of-the-art drugs. Studies of efficacy and safety of these drugs in children have lagged behind, and the full range of appropriate formulations to treat younger children are yet to be developed for both first- and second-line treatments.