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Er zijn25resultaten gevonden
Medicatieveiligheid

Sexual adverse drug reactions

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Rineke Gordijn
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Martina Teichert
  • Jaar 2020-2022
Farmacokinetiek en -dynamiek

Computational modeling of tumor growth and clonal evolution

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Anyue Yin
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Dirk Jan Moes
  • Jaar 2017-2022

Use population PK/PD modeling approach and consider evolving resistance development to better understand the development of drug resistance in anti-cancer treatments and to optimize and individualize anti-cancer treatment.

Farmacokinetiek en -dynamiek

Treosulfan pharmacokinetics and dynamics in pediatric allogeneic stem cell transplantation

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Eileen van der Stoep
  • Promoters Prof Dr Arjan Lankester Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr J Zwaveling
  • Jaar 2015-2022

Treosulfan is increasingly used in pediatric allogeneic HSCT. Pharmacokinetic data in children is sparse. Also the relationship with acute and late toxicity and clinical outcome is not clear yet. Our aim is to establish a popPK model, investiate the relationship between treosulfan exposure and outcome and to acquire knowledge about the acute and late side effects. 

Medicatieveiligheid

The metabolisation of drugs as a factor in the development of adverse drug reactions

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus N. Jessurun
  • Promoters Prof dr E.P. van Puijenbroek Prof dr R.J. van Marum
  • Co-Promoters ds Dr H.J. Derijks Dr K Grootens
  • Jaar 2018-2022

The aim of this PhD is to study the role of drug metabolism in adverse drug reactions (ADRs), an area which is not often taken into account in pharmacovigilance. The role of metabolites in ADRs is studied by focusing on (but not limiting to) a number of  therapeutic drug groups.

Medicatieveiligheid

From prescription-based monitoring towards continuous pharmaceutical care in community pharmacy

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus Ellen van Loon
  • Promoters K. Taxis M. Bouvy
  • Co-Promoters ds M. Heringa
  • Jaar 2019-2024

Onderzoeksprojekt over de mogelijkheden die de beweging naar continue
farmaceutische patiëntenzorg helpen mogelijk te maken dan wel te versnellen.

Medicatieveiligheid

Health Alliance for Prudent Prescription and Yield of Antibiotics in a Patient-centred Perspective (HAPPY PATIENT) – the role of community pharmacies

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus Maarten Lambert
  • Promoters K. Taxis L van Dijk
  • Jaar 2021-2025

European funded project to reduce the inappropriate use of antibiotics in common infectious diseases by implementing EU guidelines for the prudent use of antimicrobials in human health. Implementing the Audit Project Odense (APO) methodology in community pharmacies in 5 European countries (France, Spain, Lithuania, Poland and Greece).

Medicatieveiligheid

Pharmaceutical care for hypertension patients

  • Universiteit Rijksuniversiteit Groningen
  • Promovendus I. Treciokiene
  • Promoters K. Taxis M. Postma
  • Jaar 2015-2023

Drug utilization of antihypertensives in the Baltic countries.

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