Promotie onderzoek

Treosulfan is increasingly used in pediatric allogeneic HSCT. Pharmacokinetic data in children is sparse. Also the relationship with acute and late toxicity and clinical outcome is not clear yet. Our aim is to establish a popPK model, investiate the relationship between treosulfan exposure and outcome and to acquire knowledge about the acute and late side effects. 

Onderzoeken eHealth applicaties ter bevordeing van geneesmiddelgebruik.

Onderzoeken van de (kosten)effectiviteit van het patientgestuurd afbouwen van TKIs bij CML.

Het onderzoeken van PK/PD relaties middels farmacometrische modellen en de implicaties daarvan op de dagelijkse klinische praktijk op de afdeling oncologie.

The aim of the thesis is to identify and examine strategies regarding the preparation and administration of medication to improve medication safety in hospitals. Examined interventions:

1. central automated dose dispensing combined with barcode-assisted medication administration,
2. a pharmacy-based centralised intravenous admixture service.