Promotie onderzoek

Hospital expenditure of expensive drugs increases yearly. In addition, shortages are becoming more common. To assure access to healthcare and treatment in the future, sustainable use of expensive drugs is very important. This research aims to optimize treatment with regard to efficacy and safety, while aiming to reduce drug costs. 
 

The research focusses on several aspects related to reimbursement: factors influencing the time to reimbursement, measures to improve the time to reimbursement, differences in the clinical evidentiary requirements of oncology assessment, EMA versus HTA bodies and changes in economic evaluations of oncology drugs in time.
 

The research project aims to develop models for the prediction of disease duration in order to support personalized and cost-effective care of depression patients. Using these models, optimal treatment strategies will be analyzed. In this project, we also want to predict treatment resistant depression as a specific subgroup and conduct cost-effectiveness analyses of different psychotherapy strategies and quantify the impact of structural uncertainty and parameter uncertainty on the results of cost-effectiveness evaluations.
 

Economische aspecten van gepersonaliseerde hart- en vaatziektepreventie bij personen met type 2 Diabetes Mellitus.
 

The aim of this project is to explore the 3D printing of peadiatric medicines. 3D printing technology enables the creation of medications with a wide range of dosages, shapes, flavors, and drug combinations, all customized to meet the unique needs of individual patients and specific disease conditions. Once the optimal formulations have been developed, the 3D printed medicines will undergo clinical trials for testing.