Farmacokinetiek en -dynamiek
Pharmacokinetic and safety studies of antiretroviral formulations: expediting first and second line regimens for all children living with HIV in Africa
- Universiteit Radboud UMC Nijmegen
- Promovendus Anne Kamphuis
- Promoters David Burger, Saskia de Wildt
- Co-Promoters ds Angela Colbers
- Jaar 2022-2026
All people living with HIV need life-long treatment with antiretroviral therapy (ART). However, ART coverage in children living with HIV continues to lag behind adults and many paediatric patients in sub-Saharan Africa still do not receive optimal paediatric treatment formulations or state-of-the-art drugs. Studies of efficacy and safety of these drugs in children have lagged behind, and the full range of appropriate formulations to treat younger children are yet to be developed for both first- and second-line treatments.