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Er zijn3resultaten gevonden
Klinische farmacologie

Deprescribing of antihypertensives in the elderly

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Dimokrat Hassan
  • Promoters Patricia van den Bemt Liset van Dijk
  • Co-Promoters ds Jorie Versmissen Karin Hek
  • Jaar 2019 - 2023

The (positive) effects of antihypertensive drugs in the cardiovascular risk management are undoubted. However, like all drugs, antihypertensive drugs also have negative side-effects. Especially the elderly, are more susceptible for these adverse effects. It's not clear whether the benefits outweight the risks. So is it possible to deprescribe antihypertensive drugs and minimise risks for adverse events, while maintining blood-pressure levels in accordance with guidelines?  

Farmacogenetica

Pharmacogenetics of platinumbased chemotherapy in non-small cell lung cancer

  • Universiteit Universiteit Utrecht
  • Promovendus Corine de Jong
  • Promoters Toine Egberts
  • Co-Promoters ds Judith Herder Vera Deneer
  • Jaar 2018 - 2022

Identificeren van biomarkers, waaronder genetische variaties, die geassocieerd zijn met de effectiviteit en toxiciteit van platinumhoudende chemotherapie in de behandeling van patiënten met niet-kleincellig longcarcinoom.

Productzorg en bereiding

Pharmaceutical 3D printing: from product development to clinical assessment

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Sejad Ayyoubi
  • Promoters prof. dr. Hugo van der Kuy
  • Co-Promoters ds dr. E.J. (Liesbeth) Ruijgrok
  • Jaar 2021-2025
  1. Stress-relieving: 3D printing personalized cortisol for patients with adrenal insufficiency
  2. A novel delayed release hydrocortison formulation for patients with adrenal insufficiency
  3. Feasibility study of 10 mg 3D printed systained release hydrocortisone 
  4. Feasibility study of 3D printed delayed release hydrocortisone 
  5. RCT of novel 3D printed hydrocortisone vs standard of care in adrenal insufficiency