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Klinische farmacologie

Antimicrobiele therapie bij kinderen in Afrika

  • Universiteit Radboud UMC Nijmegen
  • Promovendus Tom Jacobs
  • Promoters David Burger
  • Co-Promoters ds Angela Colbers
  • Jaar 2019 - 2023

Onderzoek naar de farmacokinetiek van antiretrovirale middelen, tuberculose medicatie en valganciclovir in HIV-geinfecteerde kinderen. 

Farmacokinetiek en -dynamiek

The impact of continuous renal replacement therapy and hyperinflammation on the pharmacokinetics in intensive care unit patients

  • Universiteit Erasmus Medisch Centrum Rotterdam
  • Promovendus Tim Smeets
  • Promoters prof. dr. Birgit Koch prof. dr. Diederik Gommers
  • Co-Promoters ds dr. Nicole G.M. Hunfeld dr. Henrik Endeman
  • Jaar 2021-2023
  1. To study the impact of inflammation on midazolam pharmacokinetics in critically ill covid-19 patients.
  2. To study the impact of continuous renal replacement therapy on target attainment and pharmacokinetics of drugs in critically ill patients.
Klinische farmacologie

Retroperitoneal fibrosis

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Hardjit Kharagjitsing
  • Promoters Prof Dr Teun van Gelder
  • Jaar 2020-2023
Farmacogenetica

Treatment and genetics of RA

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Frank Eektimmerman
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Jesse Swen
  • Jaar 2015-2022
Farmacokinetiek en -dynamiek

Computational modeling of tumor growth and clonal evolution

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Anyue Yin
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Dirk Jan Moes
  • Jaar 2017-2022

Use population PK/PD modeling approach and consider evolving resistance development to better understand the development of drug resistance in anti-cancer treatments and to optimize and individualize anti-cancer treatment.

Klinische farmacologie

Personalised drug repositioning using gene expression

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Michel Koudijs
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Stefan Boehringer
  • Jaar 2017-2022

Drug repositioning is the application of existing drugs to new indications. We want to find out if it is possible to find new potentially effective drugs against individual tumors based on their unique gene expression patterns.

Farmacogenetica

Personalised medicine in the outpatient pharmacy

  • Universiteit Leiden Universitair Medisch Centrum
  • Promovendus Amar Levens
  • Promoters Prof Dr Henk-Jan Guchelaar
  • Co-Promoters ds Dr Jesse Swen Dr Dirk Jan Moes
  • Jaar 2021- 2025
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